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Dispersions

Unlike nanoemulsions, not all products using dispersions want particle sizes as small as possible (e.g. inhalable drugs). Others do want to create dispersions on a nano-scale to improve bioavaiability. Microfluidizer processors have unique capabilties to precisely control shear rates, enabling customers to achieve target and uniform particle sizes for a wide variety of applications:

  • Inhalable and IV drugs
  • Ink and energy (e.g. fuel cells)
  • Carbon nanotubesc
  • Composite coatings (e.g. biomass or cellulose fibers)
  • Ceramics
  • Cosmetics (e.g. clay exfoliation, mascara, coloration, sunscreen)

 

More than milling

Conventional methods for creating dispersions are not practical - they are slow and inconsistent, and can contaminate the product stream. Microfluidizer processors, however, use fixed-geometry interaction chambers to ensure highly repeatable results, with scaleability guaranteed. They also produce smaller nanoparticles, with more intense mixing and less variance, than other technologies. This enables customers, for example, to prevent inket inks from clogging printer tubes, or to create more efficient fuel cells by coating particles with a polymer that distributes the catalyst evenly.

Top-down or Bottom-up

For certain applications and particle size targets, it can be more efficient to create nanodispersions bottom-up than it is to grind down larger particles (e.g. silver). Fortunately, innovative Microfluidics Reaction Technology (MRT) is ideally suited for creating nanodispersions via continuous crystallization and chemical reactions. MRT consists of a machine with impinging jets along with process development to achieve aggressive particle size distribution goals on the nano-scale.
 

Proven Processing Results

Carbon Nanotubes - Nanodispersion in high viscosity mineral oil for use in golf clubs.

Before After
carbonnanotubes-a carbonnanotubes-b

Azithromycin using MRT

MRT crystallization achieved a z-average of 82 nm
(ranging as small as 54 nm) with narrow distribuion.

Learn More

Contact us to learn how Microfluidics can help control the particle size distribution of your dispersion.

AZ1 AZ2